Hormonal Control of Biliary Lipid Secretion in Dogs

Biliary lipid secretion in hypercholesterolemia1

A report on the effects of primary bile acid ingestion alone or in combination with plant sterols on serum cholesterol levels, biliary lipid secretion, and bile acid metabolism. Biliary bile acid and cholesterol secretion were measured in four patients with type IIa hypercholesterolemia before and after randomized treatment periods. During these periods either a bile acid mixture (cholicchenode...

Hormonal regulation of bicarbonate secretion in the biliary epithelium.

Bicarbonate excretion in bile is a major function of the biliary epithelium. It is driven by the apically located Cl-/HCO3- exchanger which is functionally coupled with a cAMP-dependent Cl- channel (CFTR). A number of hormones and/or neuropeptides with different mechanisms and at different intracellular levels regulate, in concert, the processes underlying bicarbonate excretion in the biliary e...

Physiological functions of biliary lipid secretion

Effect of phalloidin on biliary lipid secretion in rats.

1. The effect phalloidin on bile acid, phospholipid and cholesterol secretion into bile was studied in rats with bile fistulae. 2. Phalloidin, when given for 7 days, induced a significant decrease in biliary cholesterol concentration and cholesterol saturation index. Bile acid and phospholipid concentration in bile remained unchanged. This effect was less marked in animals receiving the drug fo...

The hormonal control of colleterial gland secretion.

The right and left colleterial glands of the American cockroach act together to produce the hard, tanned egg-capsule or ootheca (Pryor, 1940 a). The left gland secretes the structural protein of which the ootheca is mainly composed and in addition a glucoside of the phenolic tanning agent, 3,4-dihydroxybenzoic (protocatechuic) acid. The right gland secretes a glucosidase. When the secretions fr...